In a large bowl, combine buttermilk, hot sauce, 1/2 tsp salt, 1/2 tsp pepper, 1/2 tsp cayenne and garlic powder.
Place chicken tenders in buttermilk mixture and toss to coat. Cover and refrigerate for 1 hour.
In a 10 inch skillet, melt 2 TBSP butter over medium high heat.
Add panko breadcrumbs to skillet and cook for 4-5 minutes, stirring frequently, until crumbs are golden brown.
Transfer toasted breadcrumbs to a shallow bowl and whisk in paprika, 1/2 tsp salt and 1/2 tsp pepper.
Preheat oven to 375°
Dredge chicken tenders in breadcrumb mixture and coat completely. Place on a baking sheet lined with parchment paper.
Pour vegetables around chicken on baking sheet.
Bake for 30-35 minutes, or until the chicken reaches an internal temperature of 165°.
In a small microwaveable bowl, melt 6 TBSP butter. Stir 1/2 tsp cayenne into melted butter.
Drizzle melted butter over chicken and vegetables when you remove them from the oven